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Vitamin A and retinoids : : An update of biological aspects and clinical appications / Edited by M. A. Livrea

Tác giả : Edited by M. A. Livrea

Nhà xuất bản : Birkhauser Verlag

Năm xuất bản : 2000

Nơi xuất bản : Basel, Switzerland

Mô tả vật lý : 300 p. ; 25 cm

ISBN : 3764358823

Số phân loại : 612.399

Tùng thư : Molecular and cell biology updates

Chủ đề : 1. Cancer -- Chemotherapy. 2. Retinoids -- Physiological effect. 3. Retinoids -- Therapeutic use. 4. Skin -- Diseases -- Chemotherapy. 5. Vitamin A -- Physiological effect. 6. Vitamin A -- Therapeutic use. 7. Vitamin A.

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Tóm tắt :

Rapid progress has been made in our understanding of the molecular mechanisms of cell growth and oncogenesis during the past decade. Special attention has been given to the presentation of the frequently neglected close correlation between changes in signal transduction and metabolic pathways during oncogenesis. This book advances the knowledge of mechanisms regulating metabolism and functioning of vitamin A and offers the most recent results of research on the clinical efficiency of retinoids in skin disorders and cancer. The book presents recent findings on the regulation of cell growth in normal and neoplastic tissues by growth factors including hormones, and by the activation and inactivation of oncogenes and tumor suppressor genes, respectively. It also offers a survey of the molecular and cell biochemistry of retinoids. Basic researchers in biochemistry, pharmacology and cell biology as well as clinicians will find this book very informative and up-to-date.

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