
Selected papers of Frederick Sanger : : With commentaries / Edited by Frederick Sanger, Margaret Dowding
Tác giả : Edited by Frederick Sanger, Margaret Dowding
Nhà xuất bản : World Scientific
Năm xuất bản : 1996
Nơi xuất bản : Singapore
Mô tả vật lý : xiii, 662 p. : ill. ; 26 cm
Số phân loại : 572.633
Chủ đề : 1. Amino acid sequence. 2. Nucleotide sequence. 3. Chuỗi axit Amino. 4. Chuỗi Nucleotide. 5. Hóa chất sinh học. 6. Hóa sinh học.
Thông tin chi tiết
Tóm tắt : | These papers are mainly concerned with the development of methods for "sequencing" - that is, determination of the order of the amino acids in proteins and of nucleotides in RNA and DNA. In 1943 the position of only one amino acid in a protein (insulin) was known, and Sanger's first paper resulted in finding a second amino acid. In his final paper in 1982 he describes the determination of a DNA sequence of 48,502 nucleotides. The papers describe the steady improvements in techniques, and exciting biological results revealed by the sequences. |
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