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The way of synthesis : : evolution of design and methods for natural products / Tomás Hudlický and Josephine W. Reed

Tác giả : Tomás Hudlický and Josephine W. Reed

Nhà xuất bản : John Wiley [distributor]

Năm xuất bản : 2007

Nơi xuất bản : Chichester

Mô tả vật lý : xv, 1004 p. : ill. ; 25cm

ISBN : 9783527314447

Số phân loại : 547.2

Chủ đề : 1. Sinh tổng hợp. 2. Biosynthesis. 3. Natural products. 4. Sinh tổng hợp.

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Tóm tắt :

This two-colored textbook presents not only synthetic ways to design organic compounds, it also contains a compilation of the most important total synthesis of the last 50 years with a comparative view of multiple designs for the same targets. It explains different tactics and strategies, making it easy to apply to many problems, regardless of the synthetic question in hand. Following a historical view of the evolution of synthesis, the book goes on to look at principles and issues impacting synthesis and design as well as principles and issues of methods. The sections on comparative design cover classics in terpenes and alkaloid synthesis, while a further section covers such miscellaneous syntheses as Maytansine, Palytoxin, Brevetoxin B and Indinavir. The whole is rounded off with a look at future perspectives and, what makes this textbook extraordinairy, with personal recollections of the chemists, who synthesized these fascinating compounds

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