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Can type 2 diabetes and its associated complications be prevented or delayed in people with intermediate hyperglycaemia? / Stinton, Chris;Herath, Deshani;Parr, Janette;Mansbridge, Alice;Williams, Hannah;Rotar, Oxana;Grove, Amy;Al-Khudairy, Lena;Kudrna, Laura;A. Johnson, Samantha;Oyebode, Oyinlola;Taylor-Phillips, Sian

Tác giả : Stinton, Chris;Herath, Deshani;Parr, Janette;Mansbridge, Alice;Williams, Hannah;Rotar, Oxana;Grove, Amy;Al-Khudairy, Lena;Kudrna, Laura;A. Johnson, Samantha;Oyebode, Oyinlola;Taylor-Phillips, Sian

Nhà xuất bản : World Health Organization. Regional Office for Europe

Năm xuất bản : 2024

ISBN : 9789289061230 (PDF); 9789289061247 (print)

Tùng thư : Health Evidence Network synthesis report

Chủ đề : 1. Diabetes Mellitus, Type 2. 2. Population. 3. Public Health Practice. 4. Randomized Controlled Trial. 5. Systematic Review. 6. Publications.

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Tóm tắt :

Diabetes affects one in 11 adults in the WHO European Region. It is a key risk factor for cardiovascular diseases, kidney failure, vision loss and nerve damage. Intermediate hyperglycaemia is a state in which blood glucose levels are above the normal range but below the threshold for diabetes. It is associated with an increased risk for type 2 diabetes, obesity, cardiovascular diseases and mortality. This review assessed the effects of interventions for people with intermediate hyperglycaemia. Results from randomized controlled trials indicate that the risk of developing type 2 diabetes in people with intermediate hyperglycaemia is reduced by lifestyle and (some) pharmacological interventions. Most of the available evidence did not find a difference in mortality or other serious health outcomes for either pharmacological or lifestyle interventions. However, the follow-up periods may have been too short for health outcomes to have emerged. The current evidence suggests that the risk of developing type 2 diabetes is reduced through intervention at the point of intermediate hyperglycaemia, but that the effects of these interventions on long-term health outcomes are unclear. xii, 213 p.

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https://iris.who.int/handle/10665/378139